GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| THCA | cis | rs6504950 | 1 | rs6504949 | chr17:53050133 | STXBP4 | chr17:53046126-53241449:+ | -0.15 | -4.2 | 3.2E-5 | Breast cancer |
| THCA | cis | rs6504950 | 1 | rs6504949 | chr17:53050133 | TOM1L1 | chr17:52978052-53039328:+ | -0.13 | -3.35 | 0.000871 | Breast cancer |
| THCA | cis | rs6504950 | 1 | rs6504950 | chr17:53056471 | STXBP4 | chr17:53046126-53241449:+ | -0.15 | -4.2 | 3.2E-5 | Breast cancer |
| THCA | cis | rs6504950 | 1 | rs6504950 | chr17:53056471 | TOM1L1 | chr17:52978052-53039328:+ | -0.13 | -3.35 | 0.000871 | Breast cancer |
| THCA | cis | rs6504950 | 1 | rs6504951 | chr17:53056975 | STXBP4 | chr17:53046126-53241449:+ | -0.15 | -4.2 | 3.2E-5 | Breast cancer |
| THCA | cis | rs6504950 | 1 | rs6504951 | chr17:53056975 | TOM1L1 | chr17:52978052-53039328:+ | -0.13 | -3.35 | 0.000871 | Breast cancer |
| THCA | cis | rs9902453 | 1 | rs6505152 | chr17:28331466 | ANKRD13B | chr17:27916801-27941778:+ | -0.36 | -8.85 | 1.7E-17 | Coffee consumption (cups per day) |
| THCA | cis | rs9902453 | 1 | rs6505152 | chr17:28331466 | CORO6 | chr17:27941774-27948441:- | -0.51 | -11.7 | 5.47E-28 | Coffee consumption (cups per day) |
| THCA | cis | rs9902453 | 1 | rs6505152 | chr17:28331466 | EFCAB5 | chr17:28256874-28435469:+ | -0.6 | -11.3 | 2.02E-26 | Coffee consumption (cups per day) |
| THCA | cis | rs9902453 | 1 | rs6505152 | chr17:28331466 | GIT1 | chr17:27900487-27916610:- | -0.29 | -6.8 | 3.15E-11 | Coffee consumption (cups per day) |
| THCA | cis | rs9902453 | 1 | rs6505152 | chr17:28331466 | LRRC37B2 | chr17:28903483-28992715:+ | -0.18 | -3.84 | 0.000141 | Coffee consumption (cups per day) |
| THCA | cis | rs9902453 | 1 | rs6505152 | chr17:28331466 | SSH2 | chr17:27952965-28257018:- | -0.34 | -7.64 | 1.18E-13 | Coffee consumption (cups per day) |
| THCA | cis | rs9902453 | 1 | rs6505152 | chr17:28331466 | TP53I13 | chr17:27895739-27900174:+ | -0.2 | -5.3 | 1.81E-7 | Coffee consumption (cups per day) |
| THCA | cis | rs9902453 | 1 | rs6505158 | chr17:28403348 | ANKRD13B | chr17:27916801-27941778:+ | -0.36 | -8.87 | 1.43E-17 | Coffee consumption (cups per day) |
| THCA | cis | rs9902453 | 1 | rs6505158 | chr17:28403348 | CORO6 | chr17:27941774-27948441:- | -0.5 | -11.54 | 2.46E-27 | Coffee consumption (cups per day) |